Does extranasal colonization of the throat and perineal area with Staphylococcus aureus occur?

Does extranasal colonization of the throat and perineal area with Staphylococcus aureus occur? - Throat and perineal S. aureus carriage.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON37698

Enrollment

200

Registered

2012-05-23

Start date

2012-05-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endogenous Staphylococcus aureus infection infection with a bacterium which belongs to the normal flora of individuals

Interventions

Mupirocin treatment.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Volunteers above the age of 18 years.

Exclusion criteria

Exclusion criteria: Antibiotic usage in the last 4 weeks.

Design outcomes

Primary

Measure	Time frame
- In the first phase of the study the endpoint is to define the natural S. aureus carriage state of the nose, the throat and the perineal area over a follow-up period of 12 weeks among a cohort of volunteers. At the end of this phase those volunteers who, considering the definition (chapter 6.2 of protocol), are categorized as non-carriers for S. aureus will stop participating. The remaining volunteers will be included in the second phase of the study. - In the second phase the effect of nasal eradication of S. aureus (using nasal mupirocin) on nasal, throat and perineal carriage with S. aureus will be determined.	—

Measure

Time frame

- In the first phase of the study the endpoint is to define the natural S. aureus carriage state of the nose, the throat and the perineal area over a follow-up period of 12 weeks among a cohort of volunteers. At the end of this phase those volunteers who, considering the definition (chapter 6.2 of protocol), are categorized as non-carriers for S. aureus will stop participating. The remaining volunteers will be included in the second phase of the study. - In the second phase the effect of nasal eradication of S. aureus (using nasal mupirocin) on nasal, throat and perineal carriage with S. aureus will be determined.

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)