From fibroblasts to stem cells to motorneurons in amyotrophic lateral sclerosis and related motor neuron diseases

From fibroblasts to stem cells to motorneurons in amyotrophic lateral sclerosis and related motor neuron diseases - Stem cells in amyotrophic lateral sclerosis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON37675

Enrollment

200

Registered

2012-09-18

Start date

2012-10-03

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amyotrophic Lateral Sclerosis (ALS) motor neuron disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: For healthy controls: - Without neurological disease or a disorder similar to ALS - Age > 18 years;For patients: - Diagnosis of ALS or other ALS-mimic disorder - Age > 18 years

Exclusion criteria

Exclusion criteria: For healthy controls: - Neurological disease or a disorder similar to ALS - Age

Design outcomes

Primary

Measure	Time frame
A better understanding of the pathogenesis of ALS is essential for the development of future treatment options for patients suffering from ALS. By creating iPS-cells from fibroblasts we will develop cell lines which will be used for disease modeling, with which further research can be done into the pathogenesis of ALS.	—

Secondary

Measure	Time frame
nvt	—

Countries

Netherlands

Outcome results