use of antipsychotics use of neuroleptics
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age above 65 years start of an antipsychotic drug informed consent
Exclusion criteria
Exclusion criteria: history of venous tromboemoblism or deep venous thrombosis malignancy with treatment in the last 6 months or palliative treatment bedridden or immobilisation for more than tree days operation in the four previous weeks delirium or acute psychosis, as indication of use of antipsychotic drug use of an antipsychotic in the 6 months previous to the start of the studie other changes in medication within the 10 days of observation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Platelet activation tests 2. D-dimeer 3. Von Willebrand Factor 4. Osteoprotegerine (OPG) | — |
Secondary
| Measure | Time frame |
|---|---|
| Age (in years) Sexe (male/female) Comorbidity In case of dementia, also the seriousness of the dementia according to the Clinical Dementia Rating scale In case of Parkinson(ism), also the seriousness according to the Hoehn en Yahr criteria Medication Type antipsychotic Dosage of the antipsychotic Indication of prescribing the antipsychotic medication The medical record will be used as the source for the secundairy study parameters | — |
Countries
Netherlands
Outcome results
None listed