Tape stripping as a non-invasive in vivo model for mechanical skin damage

Tape stripping as a non-invasive in vivo model for mechanical skin damage - Tape stripping as model for skin damage

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON37654

Enrollment

186

Registered

2012-06-08

Start date

2012-11-02

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin damage Skin irritation

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adults between 18 and 65 years of age Volunteers must be willing to give a written informed consent Volunteers must be able to adhere to all requirements of the study Volunteers must have skin type I, II or III, this will be evaluated together with a dermatologist

Exclusion criteria

Exclusion criteria: Children or adolescents younger than 18 years of age Volunteers with history or signs of chronic skin diseases Volunteers with disturbed wound healing Volunteers with relevant co-morbidities and medication Volunteers exposed to large amounts of sunlight or UV-radiation in the last week

Design outcomes

Primary

Measure	Time frame
Parameters like amount of stratum corneum removal, epidermal thickness, influx of inflammatory cells and vascularisation will be studied. Further, the correlation between HE stained sections and RCM images will be investigated.	—

Countries

Netherlands

Outcome results