The effect of a low protein diet compared with a high protein diet on food reward

The effect of a low protein diet compared with a high protein diet on food reward - ProBrain

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON37647

Enrollment

Registered

2012-03-05

Start date

2012-03-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obesitas obesity overweight

Interventions

The study will consist of a 16-day fully controlled dietary intervention that will involve consumption of individualized, isoenergetic menus providing either 0.5 g protein/kg BW/day (low protein die

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Pag. 8 protocol: • Age: 18-35 years • BMI: 18.5 - 25.0 kg/m2 • Healthy (as judged by the participant)

Exclusion criteria

Exclusion criteria: Pag. 8 protocol: • Restraint eating (men: score > 2.25; women: score > 2.80) • Lack of appetite • Having difficulties with swallowing/eating • Usage of an energy restricted diet during the last two months • Weight loss or weight gain of 5 kg or more during the last two months • Stomach or bowel diseases • Kidney disorders • Diabetes, thyroid disease, other endocrine disorders • Having a history of neurological disorders • Having taste or smell disorders • Usage of daily medication other than birth control pills • Pregnant or lactating • Smoking more than one cigarette a day • Being a vegetarian • Being allergic/intolerant for products under study • Working at the division of human nutrition (WUR) • Having participated in *ProTime*, or current participation in other research from the division of Human Nutrition (WUR). • Having a contra-indication to MRI scanning (see page 9 of protocol)

Design outcomes

Primary

Measure	Time frame
Our main outcome measurement is the change in brain reward response to sight and smell of high and low protein food stimuli after the 16-day low protein and high protein diets.	—

Secondary

Measure	Time frame
• To assess the effect of a 16-day low protein diet on different aspects of food reward: the explicit liking, the explicit wanting, the implicit wanting and a forced food choice of high and low protein food using the computerized Leeds Food Preference Questionnaire (LFPQ) compared with a high protein diet. • To assess the effect of a 16-day low protein diet on protein and energy intake compared with a high protein diet.	—

Measure

Time frame

• To assess the effect of a 16-day low protein diet on different aspects of food reward: the explicit liking, the explicit wanting, the implicit wanting and a forced food choice of high and low protein food using the computerized Leeds Food Preference Questionnaire (LFPQ) compared with a high protein diet. • To assess the effect of a 16-day low protein diet on protein and energy intake compared with a high protein diet.

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)