Overgewicht en obesitas airway disease Asthma
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Children aged 6-12 years - Residential in Southern Limburg Asthma obesity group: - A BMI in the overweight/obesity range according to LMS method of Cole et al and reference values of the fourth national Growth study. A BMI-SDS of >1.1 is considered as overweight. - An asthma diagnosis of the GP or pediatrician (>=9%FEV1 reversibility after 400 µg salbutamol) and/or medication suggestive for asthma (at least one daily dosis equivalent of Short acting Beta-2agonists, Long acting Beta-2agonists or inhaled corticosteroïds). Obesity group - A BMI in the overweight/obesity range according to data of the fourth national growth study (BMI-SDS>1.1) - No asthma diagnosis of the GP or pediatrician and no symptoms and medication suggestive for asthma. Asthma group - An asthma diagnosis of the GP or pediatrician, with symptoms (>=9%FEV1 reversibility after 400 µg salbutamol) and/or medication suggestive for asthma (at least one daily dosis equivalent of Short acting Beta-2agonists, Long acting Beta-2agonists or inhaled corticosteroïds). - A BMI in the normal weight range according to data of Cole et al [31]. Healthy controls: - A BMI in the normal weight range according to data of the fourth national growth study (BMI-SDS in between -1.8 and 1.1) - No asthma diagnosis of the GP or pediatrician and no symptoms and medication suggestive for asthma.
Exclusion criteria
Exclusion criteria: - Children with Congenital malformations of the airways or other chronic lung diseases like cystic fibrosis (CF) - Children with Mental retardation or syndromes - Children with heart diseases - Children with physical limitations which make intense physical activity impossible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the step count per day. Secondary parameters are: FEV1, FVC, %reversibility, FeNO, several EBC-markers, amount of screen time/wk, amount of time spent in intense physical activity/wk and amount of time spent in active transportation/wk. | — |
Secondary
| Measure | Time frame |
|---|---|
| NVT | — |
Countries
Netherlands