Anorexia Nervosa
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients: Female, between 18 and 35 years of age, diagnosed with Anorexia Nervosa, physically non-disabled (i.e. able to perform tasks involving arm and hand movements).;Healthy controls: Female, between 18 and 35 years of age, BMI between 18.5 and 25, no current severe mental health problems, physically non-disables (i.e. able to perform tasks involving arm and hand movements).
Exclusion criteria
Exclusion criteria: Patients: Use of medication that may influence task performance due to sedative effects, drowsiness or (psycho)motor impairments, comorbid Borderline personality disorder or contact disorder, recent start of treatment, pregnancy. Healthy controls: Use of medication that may influence task performance due to sedative effects, drownsiness, or (psycho)motor impairments, pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter of the current study is the difference in size estimation of the rubber hand before and during the RHI. This measure allows us to test whether AN patients experience the rubber hand as more different in size during the RHI illusion than controls. The main endpoints of this measure are the differences in size estimations of the rubber hand before and during the RHI. To determine this endpoint we will subtract the size estimation of the 1) width of the rubber hand; 2) width of the index finger of the rubber hand; and 3) width of the wrist of the rubber hand during the RHI from the size estimation of 1) the width of the rubber hand; 2) the width of the index finger of the rubber hand; and 3) the width of the wrist of the rubber hand before the RHI. These three difference score allow us to test whether the size estimations of the rubber hand before and during the RHI differ within and between participant groups in the synchronous and a-synchronous condition. | — |
Secondary
| Measure | Time frame |
|---|---|
| In order to investigate the first secondary objective of the present study eating disorder related pathology will be assessed with two questionnaires; the Body Shape Questionnaire and the Eating Disorder Inventory II (four subscales), and by a measure of perceptual body image. The main endpoints of the questionnaires are sum of the items on both questionnaires. The main eindpoint of perceptual body image is the difference between size estimation of the own hand and the actual size of the own hand. These measures enable us to test whether there is a relation between the difference in size estimation of the RHI before and after the RHI and eating disorder related pathology. In order to investigate the second secondary objective of the current study (i.e. replicate the findings by Eshkevari, et al (2011), we will measure proprioceptive drift. This variable consists of the estimated location of the left index finger before the RHI and the estimated location of the left index finger during the RHI. In addition the embodiment score will be measured. The embodiment score consists of the sum of the ten-item embodiment questionnaire, which measure the extent of embodiment of the rubber hand during the RHI. Both variables will be calculated for both the synchronous and a-synchronous condition of the RHI. To test the third secondary objective of the study, i.e. investigate whether AN patients show a greater temperature-drop than controls, we will measure the temperature of the left hand before and after inducing the RHI. The difference score between these measurements allows us to test whether the temperature drop differs between AN patients and controls. This variable will be calculated for both the synchronous and a-synchronous condition of the RHI. | — |
Countries
Netherlands