geen aandoeningen n.v.t.
Conditions
Interventions
Twenty minutes of repetitive transcranial magnetic stimulation (rTMS) targeted
to either the supplementary motor area (SMA group) or the premotor cortex (PMC
group), or twenty minutes of sham stimul
Sponsors
Universiteit Twente
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Subjects should be 18 years or older (capable of giving informed consent), and right handed (as indicated by the Annett Handedness Inventory).
Exclusion criteria
Exclusion criteria: Subjects are excluded if they: - have a personal history of epilepsy; - have a lesion in the brain, be it vascular, traumatic, tumoral, infectious or metabolic; - have hearing problems; - might be pregnant; - have metal objects in their brain/skull; - have a cochlear implant, implanted brain electrodes or pacemaker; - suffer from a severe medical condition; - use medications that form a relative hazard for application of TMS due to a seizure threshold lowering potential; - had spinal surgery, or have drains in their spinal cord or ventricles; - have used any illegal drugs in the last month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the difference in response time on a motor sequencing task between subjects in three rTMS conditions (SMA, PMC, sham). | — |
Secondary
| Measure | Time frame |
|---|---|
| We will measure the number of correctly performed sequences in each condition for all subjects. Also, subjects will be asked to recall the sequences that they have performed during the experiment and recognize these sequence from a list of 12 alternatives. | — |
Countries
Netherlands
Outcome results
None listed