Quantitative and qualitative analysis of T cells infiltrating the skin of children suffering from graft-versus-host disease

Quantitative and qualitative analysis of T cells infiltrating the skin of children suffering from graft-versus-host disease - Analysis of T cells responsible for skin GVHD

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON37587

Enrollment

Registered

2012-05-11

Start date

2012-08-23

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

transplantatieziekte (GvHD) Graft-versus-Host Disease GvHD

Interventions

None listed

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: Pediatric patients after HSCT that have developed/are suspected of GvHD for which the physician wants to take a skin biopsy.

Exclusion criteria

Exclusion criteria: Not-pediatric, patients (or legal representatives) not willing to undergo biopsy, contra-indications for skin biopsy (allergic for topical anesthetics).

Design outcomes

Primary

Measure	Time frame
Number, phenotype and specificity of the T cells when comparing the several subgroups.	—

Secondary

Measure	Time frame
Grade of GvHD, therapy-response.	—

Countries

Netherlands

Outcome results