Neurological, visual and neurocognitive performance in pediatric HIV-1- infected patients as compared to healthy controls.

Neurological, visual and neurocognitive performance in pediatric HIV-1- infected patients as compared to healthy controls. - NOVICE

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON37553

Enrollment

Registered

2012-08-02

Start date

2012-12-28

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain disease neurologic and neuropsychologic impairment

Interventions

None listed

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: Cases: Perinatally infected with HIV Cases/controls: 8-17 years of age

Exclusion criteria

Exclusion criteria: Intracranial malignancy, history of traumatic brain injury with loss of consciousness > 30 minutes Severe psychiatric disorders MRI contra-indications (e.g. implanted active devices such as pacemakers or medication pumps, or metal splinters in eye, brain or lungs, claustrophobia)

Design outcomes

Primary

Measure	Time frame
Main endpoints are diminished neurocognitive performance, deviations in neuroimaging parameters and ophthalmological measurements, comparing HIV positive cases to healthy controls. Several CSF and blood parameters will be measured and correlated to the results of the above mentioned tests.	—

Secondary

Measure	Time frame
nvt	—

Countries

Netherlands

Outcome results