neurologische aandoening: ziekte van Parkinson Parkinson's disease
Conditions
Interventions
One hundred twenty subjects (sixty at each side) will receive a six week long
therapy intervention program consisting of integrated dual task training,four
times a week, for thirty minutes long. Twi
Sponsors
Universitair Medisch Centrum Sint Radboud
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1) Diagnosis of Parkinson's disease based on UK Brain Bank criteria; 2) Hoehn & Yahr stage II-III in the on-phase; 3) Able to walk for 10 minutes continuously (FAC>4 *); 4) Dual task interference of at least 5% using a cognitive secondary task; 5) Without cognitive impairment (MoCA > 24+MMSE>24); 6) On stable medication;;* M.K. et al. (1984) Functional Ambulation Category 4: Patient can walk independently on level ground, but requires help on stairs, slopes or uneven surfaces.
Exclusion criteria
Exclusion criteria: 1) Deep Brain stimulation; not an exclusion criteria when it is placed longer than a year ago and a stable result is being accomplished. 2) Severe medical conditions affecting gait; 3) Hearing and severe visual problems affecting testing; 4) Likely to change medication regimen; 5) Already receiving dual task training from their physiotherapist;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome measure is Dual Task (DT) gait performance. DT gait performance will be evaluated by measuring gait speed at maximum levels while performing untrained cognitive tasks. At baseline, the appropriate cognitive task (sufficient level of cognitive challenge for each patient) will be determined | — |
Secondary
| Measure | Time frame |
|---|---|
| • Cognitive performance during dual task walking; amount of errors are scored during the dual task assessment on the walkway. • Gait performance during the trained cognitive tasks; as measured by the GAITRite system. • Dual task interference outcomes; by comparing the gait performance on the single task and dual task assessment. • Single task gait performance: speed, stride length and cadence; as measured by the GAITRite system. • Single task cognitive performance (during sitting); amount of errors is scored during a single cognitive task which is similar to the cognitive task that is used in the dual task test session. | — |
Countries
Netherlands
Outcome results
None listed