Cognitive adverse effects of anti-epileptic drugs investigated using fMRI

Cognitive adverse effects of anti-epileptic drugs investigated using fMRI - Cognitive adverse effects of AEDs investigated using fMRI

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON37523

Enrollment

Registered

2012-02-29

Start date

2012-04-05

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

convulsions epilepsy

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age over 18 years old, able to give informed consent, using anti-epileptic drugs (phenytoin, topiramate, levetiracetam or lamotrigine) when investigations take place.

Exclusion criteria

Exclusion criteria: Absolute or relative contra-indications for MR scanning, unable to peform tasks in MR or unable to complete the questionnaires.

Design outcomes

Primary

Measure	Time frame
Differences between the groups on network describing MR parameters, especially fMRI, functional connectivity and spectroscopy; Relations between these parameters with their anti-epileptic drug use.	—

Secondary

Measure	Time frame
The MR parameters and anti-epileptic drug use will be correlated with neuropsychological test results and the results of the questionnaires.	—

Countries

Netherlands

Outcome results