The effects of daily neuromuscular electrical stimulation during short term one-legged knee immobilization on muscle mass in healthy young men

The effects of daily neuromuscular electrical stimulation during short term one-legged knee immobilization on muscle mass in healthy young men - ESDIM

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON37432

Enrollment

Registered

2012-02-08

Start date

2012-03-15

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

muscle metabolism disuse atrophy

Interventions

Five days of knee immobilization with or without twice daily NMES.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Male - Aged between from 18-35 years - BMI above 18.5 and below 30 kg/m2

Exclusion criteria

Exclusion criteria: - Any family history of thromboses - All co-morbidities interacting with mobility and muscle metabolism of the lower limbs (e.g. arthritis, spasticity/rigidity, all neurological disorders and paralysis). - Diagnosed impaired renal or liver function - Myocardial infarction within the last 3 years - Use of anti-coagulants

Design outcomes

Primary

Measure	Time frame
Primary: Quadriceps CSA	—

Secondary

Measure	Time frame
quadriceps lean mass, type I and II muscle fiber CSA and SC content, muscle strength.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)