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GHB neurotoxicity, brain damage due to GHB-induced coma in recreational GHB users

GHB neurotoxicity, brain damage due to GHB-induced coma in recreational GHB users - GHB neurotox

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON37414
Enrollment
60
Registered
2012-07-10
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cognitive and memory damage

Interventions

None listed

Sponsors

Academisch Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Age 18-40 years. • Participants in groups 1-3 have a life time prevalence of GHB use of 25 times or more. • Expressed willingness to participate to experimental part in AMC.

Exclusion criteria

Exclusion criteria: • Subjects/patients with epilepsy. • Heavy alcohol use (> 20 drinks) on at least one occasion in the last year. • General anaesthesia in the last year. • With respect to MRI imaging: claustrophobia; presence of non-removable metal objects, use of psychotropic medication. . Pregnant or breast-feeding mothers • Use of ketamine or speed is no exclusion criterion, but will be registered

Design outcomes

Primary

MeasureTime frame
Cognitive skills and memory in the different groups (cross-sectional). Changes in brain structures.—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)