Response evaluation after chemoradiation for advanced oropharyngeal cancer using PET-CT and MRI

Response evaluation after chemoradiation for advanced oropharyngeal cancer using PET-CT and MRI - REACTION-study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON37398

Enrollment

Registered

2012-03-21

Start date

2012-06-04

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oropharynx cancer throat cancer

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: *Oropharyngeal squamous cell carcinoma *Initially resectable *Scheduled for chemoradiation

Exclusion criteria

Exclusion criteria: *Pregnancy *Physical condition contra-indication salvage surgery *Contra-indication for MRI (i.e. claustrofobia)

Design outcomes

Primary

Measure	Time frame
The primary endpoint is accuracy with which diagnostic tests reduce the number of avoided futile EUAs.	—

Secondary

Measure	Time frame
Secondary endpoints are interobserver agreement, SUV (FDG-PET) and ADC (DW-MRI) thresholds, associated costs and burden of diagnostic procedures and health related quality of life.	—

Countries

Netherlands

Outcome results