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Glaucoma and other ocular complications in herpetic and HLA-B27 associated anterior uveitis.

Glaucoma and other ocular complications in herpetic and HLA-B27 associated anterior uveitis. - Glaucoma and other ocular complications in anterior uveitis.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON37375
Enrollment
101
Registered
2012-06-13
Start date
2012-09-06
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anterior uveitis eye inflammation

Interventions

None listed

Sponsors

Universitair Medisch Centrum Groningen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with anterior uveitis associated with herpes or HLA-B27.

Exclusion criteria

Exclusion criteria: Patients whose cause of anterior uveitis is not certain. Patients having more than one cause for anterior uveitis. Patients with other forms of uveitis than anterior uveitis. Patients who were already diagnosed with elevated IOP or glaucoma before the occurrence of uveitis.

Design outcomes

Primary

MeasureTime frame
Primary outcome measures: • Intraocular pressure at presentation of first uveitis episode. (retrospective) • Intraocular pressure at the following uveitis episodes at first visit. (retrospective) • Course of intraocular pressure during treatment and control moment of uveitis.(retrospective) • Time of onset of glaucoma (after how many episodes / active duration). (retrospective) • Use of anti-glaucomatous agents. (Only treated during IOP elevation or also between IOP elevations. The total number of glaucoma medication used, is noted.) (retrospective) • Applied glaucoma surgery. (retrospective) • Use steroid eye drops. (retrospective / present status) • Current IOP, visual fields and optic disc status. (present status) • Duration of follow-up. (retrospective)

Secondary

MeasureTime frame
Secondary outcomes: • Secondary cataract (corticosteroid-induced). (retrospective / present status) • Formation of anterior synechiae and / or posterior synechiae. (present status) • Formation of cystoid macular edema. (retrospective / present status) • Visus (present status) • Slit lamp examination: presence of iris transillumination (radial, sector), pseudoexfoliation, Krukenberg's spindle. (present status) • Central corneal thickness (pachymetry) (retrospective / present status) • Glaucoma risk factors (family history, myopia, race) (present status)

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)