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BASIS (Breast Cancer Somatic Genetics Study)

BASIS (Breast Cancer Somatic Genetics Study) - BASIS

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON37355
Enrollment
500
Registered
2012-05-21
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breastcancer

Interventions

None listed

Sponsors

Academisch Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: The tumorsubtype is ER+ HER2- Tumor has to be removed surgically

Exclusion criteria

Exclusion criteria: Tumor has been treated with preoperative radiation and/or chemotherapy

Design outcomes

Primary

MeasureTime frame
Full genome DNA sequencing and RNA expression profiling. Potential cancer genes will be further analyzed by using in situ hybridization and RT-PCR.

Secondary

MeasureTime frame
Full genome methylation analysis will be performed. mRNA en miRNA expression profiling

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)