cognitieve veroudering mild cognitive impairment mild memory loss
Conditions
Interventions
Healthy older adults and MCI patients will receive the computerized
working-memory training Cogmed QM, which runs on the participant*s PC at home.
The training consists of 25 sessions of approximate
Sponsors
Universitair Medisch Centrum Sint Radboud
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Males and females aged 20-35 (young adults group) or 60-85 (older adults group and MCI group) - MCI group: Diagnosis of amnestic Mild Cognitive Impairment according to International Working Group criteria. - Right-handed - Dutch speaking - Informed consent - Normal or corrected-to-normal vision - Access to a PC with internet connection at home (older adults group and MCI group)
Exclusion criteria
Exclusion criteria: - Estimated IQ 160/90 mmHg (use of antihypertensives are allowed) - Use of psychopharmacological drugs (anxiolytics, antidepressants, antipsychotic drugs, long-acting benzodiazepines etc.) - Current abuse of drugs or alcohol - Current participation in another study, or a specific cognitive training study within the past six months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in functional prefrontal activation as determined by oxygenated hemoglobin changes (*mol/L) induced by working-memory training. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in functional prefrontal activation as determined by deoxygenated hemoglobin changes (*mol/L) induced by working-memory training. | — |
Countries
Netherlands
Outcome results
None listed