Influence of changes in brain activity during movement observation and execution on the recovery of motor function after stroke.

Influence of changes in brain activity during movement observation and execution on the recovery of motor function after stroke. - Changes in brain activity patterns during movement after stroke.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON37259

Enrollment

Registered

2009-04-08

Start date

2010-04-01

Completion date

Unknown

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebrovascular accident (CVA) Stroke

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - First ever ischemic stroke - Unilateral cortical and/or subcortical stroke - Stroke

Exclusion criteria

Exclusion criteria: - Other (pre-existing) neurological diseases (e.g. epilepsy, tumor, paralysis) - Autism spectrum disorders, PDD, schizophrenia (or history of schizophrenia) - Instable medical health situation (cardiovascular and/or neurological) - Uncompensated hemineglect or cognitive disabilities, resulting in misunderstanding or incapability of executing instructions given - Uncorrected visual problems, i.e. not able to observe the movie on the screen

Design outcomes

Secondary

Measure	Time frame
There are no secundary study parameters	—

Primary

Measure	Time frame
The correlation between changes in motor control and motor function and cortical activity is measured by comparing the scores of the grip strength (motor control) and the Fugl-Meyer motor assessment (motor function) with the changes in activity of the cortex. The activity of the brain is summarized in topoplots showing the degree of (de)synchronization by a colorscale projected on a headmodel. Change of activity of the cortex is quantified by calculating the event related synchronization (i.e. the difference in power of the EEG between the resting and the action condition), and the Brain Symmetry Index (i.e. the symmetry of the activity between the two hemispheres).	—

Measure

Time frame

The correlation between changes in motor control and motor function and cortical activity is measured by comparing the scores of the grip strength (motor control) and the Fugl-Meyer motor assessment (motor function) with the changes in activity of the cortex. The activity of the brain is summarized in *topoplots* showing the degree of (de)synchronization by a colorscale projected on a headmodel. Change of activity of the cortex is quantified by calculating the event related synchronization (i.e. the difference in power of the EEG between the resting and the action condition), and the Brain Symmetry Index (i.e. the symmetry of the activity between the two hemispheres).

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Countries

Netherlands

Outcome results