haed and neck malignancies melanoma rectal cancer soft tissue tumours
Conditions
Interventions
None listed
Sponsors
Philips
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: •Patients planned for elective inguinal or cervical lymph node dissection, parotidectomy, rectal resection or resection of soft tissue tumour. •Written informed consent •Patients >= 18 years old
Exclusion criteria
Exclusion criteria: •Patients with suspected sensitivity to light; e.g. patients who have had photodynamic therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Several optical spectroscopy parameters of the targeted tissue will be analysed and specified. Diffuse reflectance parameters: Oxyhaemoglobin saturation, total haemoglobin content, water and fat content within the tissue as well as 2 scatter coefficients of the tissue. Fluorescence parameters: Collagen, elastin, NADH content within the tissue. The analysis of the different reflectance and fluorescence parameters will result in a specific tissue fingerprint allowing optical tissue specific characterization of nerve tissue of the hypogastric plexus. Primary Objective: In this pilot study we aim to evaluate whether optical spectroscopy is able to differentiate between nerve tissue and surrounding tissue. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary Objective: During the measurement procedure, possible improvements of the measurement hardware will be recorded and the handling during surgery will be evaluated. | — |
Countries
Netherlands
Outcome results
None listed