Niet van toepassing Niet van toepassing
Conditions
Interventions
There are two interventions:
-Honger and sated
Participants will undergo one scan while sated (a meal will
be offered to the participants by the researchers) and one scan while hungry.
-Exposure to divers types of sugars and sweeteners
during the two scans
different types of sugars and sweeteners will be offered to the participant in
a randomized order.
Sponsors
Wageningen Universiteit
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: See page 8 and 9 of the protocol -Gender: female -Age: 18-35 year -BMI: 18.5-25.0 kg/m2 -Healthy (as judged by the participant)
Exclusion criteria
Exclusion criteria: See page 9 and 10 of the protocol -Restraint eating (women: score > 2.80) -Lack of appetite -Having difficulties with swallowing/eating -Usage of an energy restricted diet during the last two months -Weight loss or weight gain of 5 kg or more during the last two months -Stomach or bowel diseases -Diabetes, thyroid disease, other endocrine disorders -Having a history of neurological disorders -Having taste or smell disorders -Usage of daily medication other than oral contraceptives or paracetamol -Being pregnant or lactating -Smoking more than one cigarette/cigar a day -Being allergic/intolerant for products under study -Exclusive consumption of *light* versions of products -Avoidance of *light* versions of products -Working at the Division of Human Nutrition (WUR) -Current participation in other research from the Division of Human Nutrition (WUR) -Having a history of or current alcohol consumption > 28 units per week -Having a contra-indication to MRI scanning
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter/endpoint is taste activation in response to exposure to different caloric and non-caloric food stimuli. | — |
Secondary
| Measure | Time frame |
|---|---|
| The 1st secondary study parameter/endpoint is taste activation in response to caloric and non-caloric stimuli during hunger and during satiety. The 2nd secondary study parameter/endpoint is the correlation between taste activation in response to exposure to caloric and non-caloric stimuli and subject characteristics like reward sensitivity and impulsivity. | — |
Countries
Netherlands
Outcome results
None listed