Kinetics of IroN in Donors

Kinetics of IroN in Donors - KIND

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON37151

Enrollment

Registered

2012-10-11

Start date

2013-02-26

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fysiologisch herstel na bloeddonatie in gezonde mannen Iron status after blood donation

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Male, 2 or less blood donations or 10 or more blood donations, BMI between 20 and 27, length at least 175 cm, age between 30 and 50, ALT and CRP normal at start

Exclusion criteria

Exclusion criteria: vegetarian, blood type O neg, HFE mutation (homozygote C282Y or compound heterozygote C282Y/H63D genotype)

Design outcomes

Primary

Measure	Time frame
Hb and red cell and reticulocyte indices (MCV, MCH, RDW, Ret Hb), serum iron parameters (iron, ferritin, transferrin, transferrin saturation, serum transferrin receptor (sTfR), zinc protoporphyrin (ZPP), hepcidin) and erythropoiesis marker (EPO).	—

Secondary

Measure	Time frame
Blood volume, number of previous donations, donation frequency	—

Countries

Netherlands

Outcome results