postprandial Lipidmetabolism in hMe subjects and healthy controls

postprandial Lipidmetabolism in hMe subjects and healthy controls - LIME study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON37127

Enrollment

Registered

2012-12-12

Start date

2013-01-10

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postprandial dyslipidimia postprandial lipidmetabolism disorder

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Male and female subjects at least 18 years of age Clinically esthablished diagnosis of HME or unaffected, healthy control willing to stop ATII/ACE inhibitors (5 days) and statin (4 weeks) before lipidload

Exclusion criteria

Exclusion criteria: Current diabetes Current pregnancy Malignancy with limited lifespan -Cardiovascular disease

Design outcomes

Primary

Measure	Time frame
Changes in postprandial trygliceride levels in HME subjects vewith either EXT1 or EXT2 mutation compared to unaffected, healthy control subjects	—

Secondary

Measure	Time frame
Changes in cardiovascular risk profile (lipidprofile, ECG changes) in HME subjects vewith either EXT1 or EXT2 mutation compared to unaffected, healthy control subjects	—

Countries

Netherlands

Outcome results