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Lymph nodes in pre-clinical and clinical arthritis

Lymph nodes in pre-clinical and clinical arthritis - geen

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON37084
Enrollment
120
Registered
2010-07-01
Start date
2008-02-01
Completion date
Unknown
Last updated
2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic joint inflammtion rheumatoid arthritis

Interventions

None listed

Sponsors

Academisch Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1) pre-clinical arthritis patients with positive anti-CCP or IgM rheumatoid factor OR 2) early arthritis patients with disease duration

Exclusion criteria

Exclusion criteria: Present use of disease modifying anti-rheumatic drugs (DMARDs)

Design outcomes

Primary

MeasureTime frame
Differences in LN cellular composition and functional aspects of lymphnodes in pre-clinical patients eventually developing RA compared to patients that do not develop RA, and of lymphnodes of early RA patients compared to non-RA patients, all compared to lymph node tissue of healthy controls.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)