Physical activity and cognition in early-onset dementia.

Physical activity and cognition in early-onset dementia. - Physical activity in early-onset dementia.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON37056

Enrollment

262

Registered

2009-11-24

Start date

2010-02-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

early-onset dementia presenile dementia

Interventions

Participants with EOD who participate in the intervention part of this study will be randomised into a 3 month enduring program: Directly Guided Aerobe Activity Program (aerobe activity, such as run

Directly Guided Flexibility Program (flexibility training and relaxation exercises)

Indirectly Guided Aerobe Activity Program (*therapy*, stimulation of aerobe activity at home).

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Main study: - Diagnosis of early-onset dementia (onset of complaints

Exclusion criteria

Exclusion criteria: Main study: - Bound to a wheelchair - Neurodegenerative diseases at which motor symptoms are the primary problems, such as M. Parkinson and M. Huntington. - Cardiovascular problems, such as severe cardiac problems or severe hypertension. - Abuse of alcohol or other substances - Trauma capitis in the medical history, at which a loss of consiousness was present of more than 15 minutes - Extended history of psychiatry (major depression , bipolar disroder, psychosis) - Severe visual problems - Severe auditive problems - Insufficient mastery of the Dutch language;Extension: same exclusion criteria

Design outcomes

Primary

Measure	Time frame
Primary study parameters in the cross-sectional study will be measures concerning physical functioning (question 1a) and measures concerning global cognitive functioning, mental speed, and executive functioning (question 1b). Primary study parameters in the intervention study will be measures concering global cognitive functioning, mental speed, instrumental activities of daily living, and quality of live.	—

Measure

Time frame

Primary study parameters in the cross-sectional study will be measures concerning physical functioning (question 1a) and measures concerning global cognitive functioning, mental speed, and executive functioning (question 1b). Primary study parameters in the intervention study will be measures concering global cognitive functioning, mental speed, instrumental activities of daily living, and quality of live.

—

Secondary

Measure	Time frame
Secundary measures concern mood and rest-activity rhythm.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)