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UPFRONT - Prospective cohort study on early identification and treatment of adaptive deficits in mild to moderate traumatic brain injury - the impact of frontal network dysfunction for longterm outcome.

UPFRONT - Prospective cohort study on early identification and treatment of adaptive deficits in mild to moderate traumatic brain injury - the impact of frontal network dysfunction for longterm outcome. - Adaptive deficits in TBI patients (UPFRONT-study)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON37031
Enrollment
2200
Registered
2012-11-20
Start date
2013-01-23
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

traumatisch hersenletsel adaptive deficit behavioral regulation

Interventions

The Cognitive Behavioral Therapy (CBT) is aimed at improving coping skills and diminishing ineffective thoughts and catastrophizing illness perception related to the TBI comprising an intervention g

Sponsors

Universitair Medisch Centrum Groningen
Lead Sponsor

Eligibility

Age
12 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with mild to moderate TBI who are admitted to the emergency department of one of the participating hospitals. All patients admitted within the one-year inclusion period will be asked to participate in the follow up study. Inclusion criteria: Project 1 - GCS scores on admission from 9-15 with loss of consciousness or Posttraumatic Amnesia. Age >15 years. Comprehension of Dutch language. Project 2 - Same as for study 1, but age range between 18-65 years. At least 3 complaints determined with a questionnaire 2 weeks postinjury comprising minimally one complaint in the cognitive domain and minimally one in the emotional/social domain (based on the actual incidence of PCS). Project 3 - age range between 18-65 years.

Exclusion criteria

Exclusion criteria: Inability to follow-up, drug or alcohol abuse, psychiatric co-morbidity, previous TBI, language barriers prohibiting understanding and completion of questionnaires.

Design outcomes

Primary

MeasureTime frame
For the intervention study the primary outcome measure is level of resumption of work or study 12 months, measured with the RTW subscale of the RRL (Van den Burg & van Zomeren, 1985).

Secondary

MeasureTime frame
-Working status defined as total days off work at 12 months -GOS-E, determined by an experienced neurologist at 12 months -Differential Outcome Scale (DOS, van der Naalt, 2000), determined at 12 months -Role resumption (RRL; Rolhervattingslijst, Spikman et al, 2010)

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)