alle organische ziekten van het onderste maagdarmstelsel organic diseases of the lower gut spastic colon (for functional bowel disease)
Conditions
Interventions
None listed
Sponsors
Zorgonderzoek Nederland (ZON)
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients with non-acute (> 2 weeks) abdominal complaints originating from the lower GI tract and with at least one of the following criteria (high risk patients): - unexplained rectal blood loss - unexplained weight loss - unexplained abdominal pain - persistant diarrhoea - altered defecation pattern - unexplained fever - sudden onset in elderly patients - abnormal results at physical examination
Exclusion criteria
Exclusion criteria: Being unable to give informed consent Age under 18 years A history of OBD Contra-indications for endoscopy Patients with a positive Triple Faeces Test (TFT-test), a test for detection of intestinal parasites.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is the presence of OBD at endoscopy. The diagnostic accuracy of symptoms and signs and the added value of the different tests - notably the calprotectine test- for OBD are quantified. The most cost-effective strategy to discriminate the patients at high risk (requiring a fast track diagnostic workup) from those at low risk (not requiring endoscopy) will be identified. | — |
Secondary
| Measure | Time frame |
|---|---|
| See primary study parameters. | — |
Countries
Netherlands
Outcome results
None listed