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Prediction of short and long term food challenge outcome in children

Prediction of short and long term food challenge outcome in children - PROOF study

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON37019
Enrollment
100
Registered
2013-02-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Voedselallergie Food allergy

Interventions

None listed

Sponsors

Universitair Medisch Centrum Utrecht
Lead Sponsor

Eligibility

Age
2 Years to 17 Years

Inclusion criteria

Inclusion criteria: - Child is between 1 * 18 years old - Suspected food allergy for peanut by: 1) Raised specific IgE for peanut and/ or positive skin prick test for peanut without previous known ingestion of the allergen, or; 2) Objective immediate type clinical signs or symptoms (within 2 hours) after ingestion of peanut or repetitive subjective clinical signs or symptoms after ingestion of peanut with or without raised specific IgE for peanut / positive skin prick test for peanut; or 3) Objective immediate type clinical signs or symptoms (within 2 hours) after the ingestion of an unknown allergen and raised specific IgE for peanut / positive skin prick test for peanut.;- Parents of the children must be able to speak, read and write Dutch language

Exclusion criteria

Exclusion criteria: - Peanut is eaten regularly in a substantial amount without clinical signs or symptoms - A previous severe life treating reaction to peanut requiring ICU submission.

Design outcomes

Secondary

MeasureTime frame
Clinical parameters measured during challenge to discriminate between children with positive and negative short term food challenge outcome Symptom Scores, VAS-scores, heart rate, saturation, breathing pattern, FEV1, blood pressure, temperature, VAS-scores, dermographism and eczema scores.

Primary

MeasureTime frame
- Differences between children with positive and children with negative short-term food challenge outcome - Differences between children with positive and children with negative long term food challenge outcome

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)