gambling addiction pathological gambling
Conditions
Interventions
None listed
Sponsors
Radboud Universiteit Nijmegen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Males volunteers between 18 and 65 years of age - Predominant right-handedness - Gambling status: - Gambling group: *pathological* or *problem* gamblers, as assessed by a score >= 4 on the SOGS questionnaire and the presence of 4 or more DSM-IV criteria for the diagnosis of pathological gambling (assessed using DIS-T) - Control group: score
Exclusion criteria
Exclusion criteria: - Current psychiatric treatment (excluding cognitive behavioural therapy) - Major depressive disorder, post-traumatic stress disorder and substance/alcohol abuse/dependence (except nicotine dependence) in the 6 months prior to the start of the study - Lifetime history of other DSM-IV axis I disorders and related psychiatric treatment - Average use of more than 4 alcoholic beverages daily. - Self-reported inability or unease to cease smoking during the whole testing session - Use of psychotropic medication, or of recreational drugs over a period of 1 week prior to each test session, and use of alcohol within the last 24 hours before each measurement. - (History of) neurological treatment - (History of) epilepsy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Baseline dopamine synthesis capacity in the striatum measured with[18F]fluoro-dopa (F-DOPA) Positron Emission Tomography (PET) - Behavioural performance on computerized tasks measuring reward and loss sensitivity | — |
Secondary
| Measure | Time frame |
|---|---|
| - Self-report questionnaires | — |
Countries
Netherlands
Outcome results
None listed