Parkinson's Disease
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Sint Radboud
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age 60-85 years Diagnosis Parkinson*s Disease UKBB Hoehn and Yahr stage II-III (on medication) 2 or more falls within the 6 months prior to the study Able to walk at least 5 minutes unassisted (walking aid allowed) Deep Brain Stimulation parameters and medication stable for at least one month
Exclusion criteria
Exclusion criteria: Psychiatric co-morbidities (e.g., major depression - DSM IV criteria) History of stroke, traumatic brain injury, brain tumor or other neurological disorders Acute lower back or lower extremity pain, musculoskeletal injuries, peripheral neuropathy which restricts gait Clinical diagnosis of dementia (e.g., Alzheimer*s disease, vascular dementia) Severe freezing precluding safe participation Unable to comply with testing protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The signal-to-noise ratio of the PortaLite. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in OxyHb, DeoxyHb, and total Hb in µmol/L from baseline to mean maximum value of a certain task measured with fNIRS Subjective perceived exertion is measure with a questionnaire (Borg schaal RPE) | — |
Countries
Netherlands
Outcome results
None listed