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Creatine kinase and blood pressure response

Creatine kinase and blood pressure response - Creatine kinase and blood pressure response

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON37003
Enrollment
100
Registered
2012-07-25
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

high blood pressure Hypertension

Interventions

None listed

Sponsors

Academisch Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Ambulatory adult subjects age 18-60 years, with newly detected hypertension stage I and II in primary care (SBP/DBP * 140/90 and SBP/DBP

Exclusion criteria

Exclusion criteria: No rest during the last 3 days, treated hypertension, severe (SBP * 180 mm Hg) hypertension, secondary hypertension, (history of) cardiovascular disease including TIA and stroke, myocardial infarction, angina, BMI>/= 30 kg/m2, diabetes mellitus, lipid spectrum abnormalities, thyroid, kidney, or liver abnormalities; CK-increasing drugs including statins; neuromuscular or endocrine disorders; vasculitis; HIV infection; infectious hepatitis.

Design outcomes

Primary

MeasureTime frame
The difference in blood pressure response after 3 weeks of treatment in relation to baseline serum CK.—

Secondary

MeasureTime frame
The difference between serum CK activity at baseline and after 3 weeks of treatment with antihypertensive drugs.—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)