LOw versus COnventional Tidal Volumes during One-lung Ventilation for Minimally Invasive Esophagectomy - A Randomized Controlled Trial

LOw versus COnventional Tidal Volumes during One-lung Ventilation for Minimally Invasive Esophagectomy - A Randomized Controlled Trial - LOCO-trial

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON37002

Enrollment

Registered

2012-10-10

Start date

2014-04-02

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Lung Injury lung damage

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: patients who will undergo an esophagectomy

Exclusion criteria

Exclusion criteria: Patients

Design outcomes

Primary

Measure	Time frame
The main endpoints of this study are markers of pulmonary inflammation and coagulation, including cytokines and chemokines, neutrophil influx, markers of apoptosis, and markers of coagulation and fibrinolysis in lavage fluids obtained at the beginning and at the end of surgery.	—

Secondary

Measure	Time frame
Secondary endpoints include duration of postoperative mechanical ventilation, length of stay in intensive care unit and hospital, incidence of postoperative pulmonary complications and mortality.	—

Countries

Netherlands

Outcome results