Ex vivo clot lysis measurements in blood samples of healthy volunteers.

Ex vivo clot lysis measurements in blood samples of healthy volunteers. - ROTEM-LYSIS study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON36990

Enrollment

Registered

2012-08-22

Start date

2013-01-28

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperfibrinolyse increased bloodclot breakdown

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Healthy volunteers aged 18-40 years.

Exclusion criteria

Exclusion criteria: anticoagulant or antiplatelet medication, pregnancy, history of hematologic disorders, history of deep venous thrombosis of pulmonary embolism

Design outcomes

Primary

Measure	Time frame
The main study parameter/endpoint is the Lysis onset time (time to the start of hyperfibrinolysis)	—

Secondary

Measure	Time frame
Secondary study parameters/endpoints are: Blood coagulation (INTEM, EXTEM, APTEM and FIBTEM) and fibrinolytic parameters (Maximum lysis (ML), Lysis Index at 30 and 45 minutes after clot formation (LI30, LI45) and lysis time (LT) and platelet aggregation index	—

Countries

Netherlands

Outcome results