acute confusion
Conditions
Interventions
None listed
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: ·Age 65 years or older ·Admitted to the rehabilitation ward of Verpleeghuis Laurens Antonius Binnenweg, Rotterdam. ·Diagnosis of delirium made at or during admission (DSM IV 293.0). ·Informed consent to participate in the study, signed by the patient or the legal representative. -Consent tot participate can also be given at the end of the study (if consent is not given, the CRF will be deleted).
Exclusion criteria
Exclusion criteria: ·Diagnosed with a severe, instable medical condition other than the reason for admission ·Contra-indication for the use of haloperidol ·Known neuroleptic malignant syndrome ·Tardive dyskinesia ·Lewy-body dementia ·Ongoing treatment with an antipsychotic other than haloperidol ·Severe dementia defined as an MMSE-score of
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary: The severity and clinical outcome of the delirium in relation to the biochemical parameters. The end of delirium is defined as the resolution of delirium symptoms on the DOS scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secundary: 1 DRS-R-98 scale (severity delirium) and MMSE score at the assessment moments. 2 The concentration of HVA and neopterin in plasma. 3 The concentration of interleukine-6 and CRP in the serum. | — |
Countries
Netherlands
Outcome results
None listed