Non- invasive prenatal diagnosis using cell-free fetal DNA (cffDNA) in maternal plasma

Non- invasive prenatal diagnosis using cell-free fetal DNA (cffDNA) in maternal plasma - NIPD

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON36898

Enrollment

2250

Registered

2012-08-31

Start date

2012-10-01

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

congenital anomalies down syndrome

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Pregnant women who have chosen for an invasive prenatal diagnostic test Vital pregnancy

Exclusion criteria

Exclusion criteria: patient is unable to understand information and give informede consent e.g. due to language barrier; pregnant woman with chromosome anomaly; age younger than 18 yrs

Design outcomes

Primary

Measure	Time frame
Feasability of non-invasive foetal aneuploidy testing in the UMCU, technical performance, technical failures, throughput, turnaround time and costs, sensitivity in a high risk population	—

Secondary

Measure	Time frame
-Critical parameters influencing the amount of foetal DNA in the maternal plasma such as maternal weight, gestational age and obstetric complications	—

Countries

Netherlands

Outcome results