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Cognitive impairment following cardiac arrest and Target Temperature Management (A sub-study of the TTM Trial)

Cognitive impairment following cardiac arrest and Target Temperature Management (A sub-study of the TTM Trial) - Cognitive impairment following cardiac arrest

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON36855
Enrollment
85
Registered
2012-12-12
Start date
2013-03-12
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cognitive disorders memory and concentration disturbances

Interventions

None listed

Sponsors

Academisch Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. TTM study patients who are alive at six-month follow-up and give consent to the cognitive sub-study 2. Informants (usually a relative or close friend/caregiver) of the patient above (1) who give consent to the cognitive sub-study 3. STEMI patients at the given centre, the sex-matched patient who best fits in age to the TMM patient above (1) with a similar date of infarct who gives consent to the cognitive sub-study 4. Informants (usually a relative or close friend/caregiver) of 3 above who give consent to participate.

Exclusion criteria

Exclusion criteria: The same exclusion criteria as for the main TTM study with the addition that control patients should not have a history of cardiac arrest. Exclusion criteria TTM study: Conscious patients, pregnancy, out-of-hospital cardiac arrest of presumed non-cardiac cause, cardiac arrest after arrival in hospital, known bleeding diathesis, suspected or confirmed acute intracranial bleeding, suspected or confirmed acute stroke, temperature on admission 240 minutes from ROSC to randomisation, no informed consent.

Design outcomes

Primary

MeasureTime frame
Comparing scores on cognitive test scales between patients after cardiac arrest treated with 33 or 36 degrees and patients after myocardial infarction.

Secondary

MeasureTime frame
Comparing the intensity of care for the carers between patients after cardiac arrest and patients after myocardial infarction

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)