The postcoital test in WHO class II anovulatory women; useful or redundant? a prospective follow up study

The postcoital test in WHO class II anovulatory women; useful or redundant? a prospective follow up study - postcoital test and anovulation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON36839

Enrollment

250

Registered

2009-04-01

Start date

2009-06-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anovulation postcoital test

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - WHO class II anovulatory women who ovulate following use of incremental CC doses from 50-150 mg starting on day 3-5 during 5 days of the cycle. - normal serum prolactin (0,05 - 0,80 IU/l, and TSH (0,4-4,0 mU/l - age 18 years or older - total motial sperm count above 1 million, according the modified criteria of the WHO

Exclusion criteria

Exclusion criteria: - anovulatory on CC 150 mg / day - known bilateral tubel pathology

Design outcomes

Primary

Measure	Time frame
Pregnancy rates in women with a positive compared to pregnancy rates in women with a negative postcoital test within a time horizon of six months	—

Secondary

Measure	Time frame
• Positive pregnancy test • occurrence of ovulation • total number of postcoital tests performed • median time to pregnancy in the two groups. • clinical pregnancy, defined as any registerd heart beath at sonography • miscarriage, defined as loss of an intra uterine pregnancy (confirmed by ultrasound or histologic examination) before the 20th week of pregnancy. • multiple pregnancy, defined as a registered heart beath of at least two fetuses at 12 weeks of gestation • costs	—

Measure

Time frame

• Positive pregnancy test • occurrence of ovulation • total number of postcoital tests performed • median time to pregnancy in the two groups. • clinical pregnancy, defined as any registerd heart beath at sonography • miscarriage, defined as loss of an intra uterine pregnancy (confirmed by ultrasound or histologic examination) before the 20th week of pregnancy. • multiple pregnancy, defined as a registered heart beath of at least two fetuses at 12 weeks of gestation • costs

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Countries

Netherlands

Outcome results