biliary pancreatitis
Conditions
Interventions
A) Laparoscopic cholecystectomy within 72h after randomization, versus
B) Laparoscopic cholecystectomy 25-30 days after randomization.
Patients are randomized at that time the treating physician feel
Sponsors
Universitair Medisch Centrum Sint Radboud
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - age 18 years or older - mild (non-severe) biliary pancreatitis, without sterile pancreatic necrosis and/or peripancreatic collections. - first episode of pancreatitis - written and oral informed consent
Exclusion criteria
Exclusion criteria: - patients 75 years with ASA III - ASA IV and V patients - patients with history of alcohol abuse or chronic pancreatitis - mild pancreatitis with sterile pancreatic necrosis and/or peripancreatic collections - severe pancreatitis: persistent (>48hrs) organ failure or necrotizing pancreatitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute re-admission for biliary events (recurrent biliary pancreatitis, acute cholecystitis, choledocholithiasis mandating ERCP or biliary colics). | — |
Secondary
| Measure | Time frame |
|---|---|
| - patient satisfaction, medical and indirect costs in terms of volumes of resource utilization in relation to outcome (cost-effectiveness analysis) - individual components of the primary endpoint: number of biliary colics after randomization, length of stay, difficulty of operation (VAS), duration and complications of cholecystectomy, conversion rate of laparoscopic to open cholecystectomy, length of stay, mortality. | — |
Countries
Netherlands
Outcome results
None listed