hepatocellular carcinoma livercancer
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. 18 years of age or older 2. Signed informed consent 3. Affirmed or suspected diagnosis of HCC based on current standard of care and guidelines 4. Expected (partial) treatment and follow-up at the AMC
Exclusion criteria
Exclusion criteria: Exclusioncriteria in regard to the multiphase CT scan combined with the PETscan include: 1.1. Renal impairment and allergy to the contrast agent. These patients undergo pre-treatment according to the AMC radiology protocol, after which the combined FCH PET / (multiphase) CT scan will be performed. 1.2. If patients cannot undergo the multiphase CT scan, an MRI is performed instead and FCH PET/CT is made with a low dose CT scan and no contrast is used. 1.3. If however no imaging studies with CT or MR are possible, because of contraindications against both imaging modalities, patient is excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| For further details see - Protocol section: 2 - 1. Sensitivity and specificity of the FCH PET/CT scan ( in reference to current golden standard of: ) - Histological outcome (and differentiation of the tumor) OR: - Outcome of imaging results corresponding with HCC | — |
Secondary
| Measure | Time frame |
|---|---|
| For further details see - Protocol section: 2 - 1. Diagnosis of HCC, spread of the disease or metastatic disease in an earlier stage, compared to diagnosis with conventional imaging modalities. 2. Change in treatment 3. Differentiation grade of the HCC based on the SUV-ratio (golden standard is histological outcome) | — |
Countries
Netherlands
Outcome results
None listed