Protection against ischemia-reperfusion injury (I/RI) by ischemic postconditioning in non-heart beating kidney transplantation

Protection against ischemia-reperfusion injury (I/RI) by ischemic postconditioning in non-heart beating kidney transplantation - Postconditioning to prevent I/RI in NHB-Kidney transplantation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON36716

Enrollment

Registered

2011-07-12

Start date

2011-11-01

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ischemie tgv transplantatieprocedure renal ischemia/reperfusion injury temporary lack of oxygen in the kidney due to tranplantation

Interventions

In the experimental procedure, patients will undergo three times of postconditioning during 1 minute (ie 3x 1 minute of clamping the artery)

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: All people with ESRD receiving a NHB-donorkidney

Exclusion criteria

Exclusion criteria: Younger than 18 years Patients with need of therapeutical dosage of anticoagulants (Heparin or nadroparine) needed during surgery.

Design outcomes

Primary

Measure	Time frame
Need for dialysis after surgery, duration of need for dialysis, number of dialysis.	—

Secondary

Measure	Time frame
Serum creatinine and clearance after 1, 2, 3, 4 en 12 weeks	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)