What happens to human information processing during anesthesia: the effect of a sub-anesthetic dose of S-Ketamine

What happens to human information processing during anesthesia: the effect of a sub-anesthetic dose of S-Ketamine - Effects of S-Ketamine on Information processing

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON36679

Enrollment

Registered

2012-01-12

Start date

2012-05-07

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

geen aandoening, neurologische werking van anesthesie Anesthesia loss of consciousness

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: -Male, aged between 18-30 years;-corrected to normal vision;-Written informed consent.;-Screening for fMRI;-Psychiatric Screening;-Screening contra indications S-Ketamine

Exclusion criteria

Exclusion criteria: - Inability to speak Dutch or English;- Drug or alcohol abuse over a period of six months prior to the experiment;- History of closed-head injury;- With respect to MRI imaging: claustrophobia; presence of non-removable metal objects, use of psychotropic medication.;- Multiple serious drug allergies;- Use of psychopharmaca.;- Serious neurological or psychiatric disorders;- Recreational psychotrope drugs or psychoactive drugs use in the past 30 days;- Colour blindness;

Design outcomes

Primary

Measure	Time frame
(a) fMRI, BOLD activation patterns, (b) cognitive task performance (visual short-term memory, motion induced blindness, backward masking)	—

Secondary

Measure	Time frame
nvt	—

Countries

Netherlands

Outcome results