high glucose levels insulin resistance
Conditions
Interventions
The volunteers will follow 3 times a certain activity program for 4 days. These
activity programs are:
- Sitting: 14 hours sitting, 2 hours of everyday activities (standing and
walking), 8 hours of
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Person, 18-60 years old - BMI 20.0 - 30.0 kg/m2 - Exercise: maximum 1 hour/ week,
Exclusion criteria
Exclusion criteria: - Cardiovascular diseases - Known diabetes mellitus type 1 and 2 or fasting glucose > 6.9 mmol/L - Other diseases that make physical activity difficult - Alcohol, a mean of > 2 consumptions/day (in the past 3 months) - Illegal drug use and cannabis use (in the past 3 months) - Medication use, other than contraception (in the past 3 months) - Triglycerides > 3.0 mmol/L
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change in - glucose - insuline of the activity program walking compared to sitting, and the activity program sitting/biking compared to sitting. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Area under the curve of glucose and insuline of the activity program walking compared to sitting, and the activity program sitting/biking compared to sitting. - Total cholesterol, HDL, LDL, triglyceriden, apoB en apoA of the activity program walking compared to sitting, and the activity program sitting/biking compared to sitting. - The amount of minutes sitting/ walking/ standing per day per activity program - Energy expenditure per day per activity program | — |
Countries
Netherlands
Outcome results
None listed