Physical and emotional well-being and cognitive functioning: the PREDICT-MR study

Physical and emotional well-being and cognitive functioning: the PREDICT-MR study - Well-being and cognitive functioning: the PREDICT-MR study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON36665

Enrollment

250

Registered

2010-09-28

Start date

2010-10-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression mood disorder. Cognitive impairment

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1) All participants who were diagnosed with major depressive disorder in one or more measurements of the PREDICT study (03-177/O). 2) Participants without a diagnosis of major depressive disorder on any of the PREDICT measurements. 3) All PREDICT participants of 65 years or older.

Exclusion criteria

Exclusion criteria: Contra-indications for MRI scan (metals in the body, claustrophobia, pregnancy). Dementia, psychosis, terminally ill, or physically unable to come to the UMCU as diagnosed by the general practitioner of the participant.

Design outcomes

Primary

Measure	Time frame
Outcome variables for research question 1 are the volume of the hippocampus and total brain volume on MRI. Outcome variables for research question 2 are the small vessels on MRI.	—

Secondary

Measure	Time frame
Hypothalamic-pituitary-adrenal (HPA) axis, antidepressant medication, cognitive functioning.	—

Countries

Netherlands

Outcome results