lower respiratory tract infections pneumonia
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1.Male or female adults aged 50 years or older 2.Registered with a GP who is participating in the study 3.an acute cough lasting for at least 3 days 4.Symptoms/signs suggestive of CAP or other LRTI (see protocol section 2: Definitions) 5.able to fill in a diary
Exclusion criteria
Exclusion criteria: 1.Residence in a nursing home, long-term care facility or other institution, with requirement of semiskilled nursing care. 2.Immune deficiency or suppression, defined as presence of immunocompromising disease or chronic use of immunosuppressive drugs (for prednisone low doses are allowed). 3. Hospitalisation within 7 days preceding date of inclusion 4. Severity of illness requiring hospitalisation on date of inclusion 5. Use of systemic antibiotic drugs within 14 days preceding date of inclusion See protocol paragraph 5.3 Exclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint: duration of symptoms of CAP and other LRTI. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints: complications of CAP and other LRTI, quality of life and daily activities, number of infections with Streptococcus pneumoniae, number of infections with other bacterial pathogens (Haemophilus influenzae, Moraxella catharralis, Mycoplasma pneumoniae). | — |
Countries
Netherlands
Outcome results
None listed