EXIST: Physical exercise to improve fitness and combat fatigue in patients with Multiple Myeloma or (non-) Hodgkin*s lymphoma after high dose chemotherapy and autologous stem cell transplantation.

EXIST: Physical exercise to improve fitness and combat fatigue in patients with Multiple Myeloma or (non-) Hodgkin*s lymphoma after high dose chemotherapy and autologous stem cell transplantation. - EXIST

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON36504

Enrollment

125

Registered

2010-09-17

Start date

2010-05-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

(Non-)Hodgkins lymphoma multiple myeloma

Interventions

The intervention will start 6-12 weeks after SCT and will consist of an 18-week supervised high-intensity exercise program (2x/wk aerobic and resistance exercise). 3 booster sessions at increasing i

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: -diagnosed with multiple myeloma in first line or or with HL/NHL in first line or first relapse, who have undergone HDC and autologous SCT 6 to 12 weeks ago or who where recently (

Exclusion criteria

Exclusion criteria: -tandem autologous-allogeneic stem cell transplantation -Severe cognitive impairment; -Severe emotional instability; -Insufficient mastery of the Dutch language; -Presence of extensive osteolytic lesions with risk of fracture; -Serious cardiopulmonary and cardiovascular conditions; -Other disabling comorbidity interfering with the intervention program or influencing outcome parameters (a.o. having a pacemaker , epileptic seizures and poorly regulated diabetes mellitus); -Severe infections; -Relapse/progression of disease.

Design outcomes

Primary

Measure	Time frame
primary outcome variables are fatigue, cardiorespiratory fitness and muscle strength.	—

Secondary

Measure	Time frame
Secondary outcome variables include body composition and bone mineral density, health-related quality of life, physical activity level, satisfaction with the intervention, mood disturbances, functioning in daily life and return to work.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)