Vitamin D supplementation in elderly nursing home residents: daily supplementation compared to a loading dose and monthly supplementation, a randomised trial

Vitamin D supplementation in elderly nursing home residents: daily supplementation compared to a loading dose and monthly supplementation, a randomised trial - VIDIN

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON36493

Enrollment

Registered

2011-02-03

Start date

2011-05-24

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitamine deficienties Vitamin D deficiency

Interventions

Group 1a. loading dose based on body weight and baseline serum 25(OH)D level + 50.000 IU vit D3/month consolidation therapy. Groep 1b. loading dose based on body weight and baseline serum 25(OH)D lev

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Long term indication for living in a residential home for the elderly Age > 65 years Vitamin D deficiency (serum 25- hydroxycholecholecalciferol (25(OH) D3

Exclusion criteria

Exclusion criteria: Hypercalcemia (serum Ca > 2.60 mmol/l) Hyperfosfatemia (serum PO4>2.0 mmol/l) Ca x PO4 > 4.5 Life expectancy 400 IE vit D Renal dysfunction GFR

Design outcomes

Primary

Measure	Time frame
Proportion of patients achieving and maintaining an adequate serum 25(OH)D level (75 -150 nmol/l).	—

Secondary

Measure	Time frame
Proportion of patients developing a serum 25(OH)D level > 220 nmol/l. Percentage of patients achieving an adequate serum 25(OH)D level, with the use of a loading dose, after 5 weeks Handgrip strength. Distance achieved in a 2 minute walk test.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)