Insomnia
Conditions
Interventions
Acetaminophen 1000 mg once daily versus placebo
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Aged * 65 years Subjective sleep problems during > 1 month, at least once a week Patients must be willing and medically able to receive therapy according to the protocol for the duration of the study Patients must be able to give informed consent
Exclusion criteria
Exclusion criteria: Patients using acetaminophen chronically because of pain or who have an indication to start with it (VAS score > 6). Patients, men and women, who have 120 U/l Suicidal tendencies according to the attending physician Alcohol abuse > 4 units/day
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint will be the self-reported sleep problems at the end of follow-up, measured by means of the Insomnia Severity Index (ISI). | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep efficiency, sleep onset latency, wake after sleep onset, early morning awakening, time in bed, total sleep time, registered in a sleep diary Mark for their nights rest Adverse effects | — |
Countries
Netherlands
Outcome results
None listed