The effects of plant stanols on the immune function of asthma patients

The effects of plant stanols on the immune function of asthma patients - asthma vaccination study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON36451

Enrollment

Registered

2010-06-21

Start date

2010-10-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

allergy Asthma

Interventions

During the first two weeks of the study (the run-in period) all participants receive control yoghurts without added plant stanol esters. Directly after these two weeks, the intervention period start

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Asthma Age between 18 and 70 Men and women Specific anti-hepatitis A virus antibody titers

Exclusion criteria

Exclusion criteria: - Current asthmatic exacerbations, i.e. use of prednisone or pneumoia - Other immune-related pathology, e.g. autoimmune diseases, diabetes, HTLV, HIV, other inflammatory diseases than asthma. - Previously being vaccinated against hepatitis A - Pregnancy or lactation - Impaired liver and kidney function - Use of immunosuppressive medication - Allergy to neomycin - Throbocytopenia

Design outcomes

Primary

Measure	Time frame
Specific anti-HAV antibody titers after vaccination	—

Secondary

Measure	Time frame
Phagocytic capacity of neutrophils; NK-cell activity; Th1 and Th2 cytokine production profiles by PHA stimulated PMBCs.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)