Extended metabolic phenotyping of subjects undergoing bariatric surgery

Extended metabolic phenotyping of subjects undergoing bariatric surgery - Metabolic phenotyping bariatric patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON36449

Enrollment

1200

Registered

2011-06-14

Start date

2011-04-01

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

'obesity'

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Scheduled for malabsorptive bariatric surgery in one of the participating centers Aged 18-65 years Stable weight for 3 months prior to inclusion

Exclusion criteria

Exclusion criteria: Major bleeding disorder Renal insufficiency (creatinine > 150 umol/L), liver enzymes > 3x ULN Unable to read or speak the Dutch language

Design outcomes

Primary

Measure	Time frame
Predictive value of pre-operative variables to weight loss expressed as percentage excess weight loss, reversal of metabolic complications of obesity, quality of life and postoperative complications; eating behavior and quality of life before and after bariatric surgery; pre-operative metabolic variables in plasma and tissue (adipose tissue and liver) correlated with metabolic health c.q. markers of the metabolic syndrome	—

Measure

Time frame

Predictive value of pre-operative variables to weight loss expressed as percentage excess weight loss, reversal of metabolic complications of obesity, quality of life and postoperative complications; eating behavior and quality of life before and after bariatric surgery; pre-operative metabolic variables in plasma and tissue (adipose tissue and liver) correlated with metabolic health c.q. markers of the metabolic syndrome

—

Secondary

Measure	Time frame
Prevalence of hypertension and metabolic complications of obesity before and after bariatric surgery; association of eating behavior with polymorphisms involved in appetite regulation and markers of pre-operative metabolic health.	—

Countries

Netherlands

Outcome results