Chronic disease in Immune Thrombocytopenia of Childhood

Chronic disease in Immune Thrombocytopenia of Childhood - The CIN-KID study: Chronic ITP in the Netherlands in Kids

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON36447

Enrollment

Registered

2011-05-12

Start date

2011-05-31

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

immune thrombocytopenic purpura platelet destruction by antibodies

Interventions

None listed

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: Age 1-17 years ITP lasting for more than 12 months Visting a pediatric hematologist

Exclusion criteria

Exclusion criteria: Clinical features that are not compatible with the diagnosis of chronic ITP, for example the presence of other autoimmune phenomena, other cytopenias besides thrombocytopenia (e.g. Hb

Design outcomes

Primary

Measure	Time frame
The main study parameter is the correlation between platelet function parameters and clinical bleeding tendency in children with chronic ITP.	—

Secondary

Measure	Time frame
Secondary study parameters are 1) quantity and function of regulatory T cells in children with long lasting chronic ITP, 2) response to treatment(s) given in patients with chronic ITP and biological parameters that may be related to this response, 3) HR-QoL in children with chronic ITP and their parents.	—

Countries

Netherlands

Outcome results